Personalized Oncogenomics: Clinical Experience with Malignant Peritoneal Mesothelioma Using Whole Genome Sequencing
(A)Axial CT scan showing peritoneal-based pelvic mass. (B) Abdominal fluid aspiration biopsy showing papillary mesothelial proliferation (H&E stain on cell block preparation, 40X magnification). (C) Omental disease sampled at cytoreductive surgery showing malignant mesothelial cells forming gland-like structures, papillae, with spindle cell formation and sarcomatoid features. No treatment effect is appreciable (H&E 40X).