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Down-Regulation of KCC2 Expression and Phosphorylation in Motoneurons, and Increases the Number of in Primary Afferent Projections to Motoneurons in Mice with Post-Stroke Spasticity

Figure 3

Changes in H reflex RDDs after stroke.

A: RDDs of the H reflexes at baseline (pre-stroke). B: Changes in RDDs of the H reflex 7 d post-stroke in sham and stroke animals. Data are presented as percentages relative to the mean amplitude at 0.1 Hz in the same test. C: Changes in RDDs of the H reflex with 5 Hz stimulation on the affected and non-affected sides in stroke and sham mice. Error bars indicate S.E.M. One-way ANOVA with post hoc Tukey-Kramer tests, ##p<0.01, between stroke-affected and sham-affected sides, *p<0.05 and **p<0.01, between stroke-affected and sham non-affected sides, †p<0.05 and ††p<0.01, between stroke-affected and stroke non-affected, §p<0.05, between stroke non-affected and sham-affected sides.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0114328.g003