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Down-Regulation of KCC2 Expression and Phosphorylation in Motoneurons, and Increases the Number of in Primary Afferent Projections to Motoneurons in Mice with Post-Stroke Spasticity

Figure 1

Photothrombotic stroke lesion in the left rostral and caudal forelimb motor cortex.

A: Picture of a lesion at 7 d after stroke. B: A tracing of lesion areas (7 d post-stroke, n = 6). C: Nissl staining of coronal sections of the brain at 7 d post-stroke. The left rostral and caudal forelimb motor cortex show specific injuries. The mean injury volume was 5.13±1.23 mm3 (n = 6).

Figure 1

doi: https://doi.org/10.1371/journal.pone.0114328.g001