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Bioartificial Heart: A Human-Sized Porcine Model – The Way Ahead

Figure 2

Representative images of a porcine heart before (A) and after (B) decellularization with sodium dodecyl sulfate (SDS).

All structures including the coronary vasculature (B, red arrow) are preserved. Hematoxylin and eosin (HE) staining of ventricular tissue before (C) and after perfusion decellularization (D) showing no remnant nuclear structures after treatment with SDS, with maintained extracellular matrix and coronary vessels (D, black arrow). Scale bars, 200 µm.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0111591.g002