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Hyperglycemia Promotes K-Ras-Induced Lung Tumorigenesis through BASCs Amplification

Figure 5

Analysis of BASCs expansion.

A. Immunohistochemical analysis of CC10 and SP-C in terminal bronchioles of STZ-K-RasV12 (i, ii) and untreated-K-RasV12 (iii, iv) mice. Magnification 200×. Calibration bar: 50 µm. B. Bar graph indicates percentage of terminal bronchioles with 1 or more BASCs at early and late time (STZ-K-RasV12 vs STZ-WT: *p<0,01 by X2 test).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0105550.g005