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Increased Iron Sequestration in Alveolar Macrophages in Chronic Obtructive Pulmonary Disease

Figure 7

In BAL cells, expression of proteins involved in iron metabolism correlate with airflow limitation.

(A–J) Correlation between the expression of genes encoding proteins involved in iron metabolism in BAL cells, as determined by RT-PCR, and airflow limitation was assessed in 8 non smokers without COPD, 8 smokers without COPD and 10 GOLD 1–3 COPD subjects.Three reference genes (GAPDH, HPRT1 and PPIA) were used for normalization. (Spearman rank correlation).

Figure 7