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Alpha-Lipoic Acid Reduces LDL-Particle Number and PCSK9 Concentrations in High-Fat Fed Obese Zucker Rats

Figure 7

Expression of skeletal muscle fatty acid uptake and oxidation markers in Zucker rats fed a high fat (HF) diet or the HF diet supplemented with 0.25% α-lipoic acid (HF-LA) for 30 days.

(A) Total lipase activity in serum and muscle total protein tissue extracts (n = 6 HF; 5 LA); (B) carnitine palmitoyltransferase I (CPT1β). *, denotes a significant difference (p<0.05). All data normalized to β-actin and expressed relative to HF group; n = 8/group.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0090863.g007