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The CO-Regulation Database (CORD): A Tool to Identify Coordinately Expressed Genes

Figure 3

CORD results for CDKN2A.

A) CDKN2A encoding p16 plays a significant role in the cell cycle by regulating the initiation of DNA replication. A simplified diagram shows select genes that play a major role in the cell cycle. CORD identifies many genes known to play major roles in the cell cycle by determining genes co-regulated with CDKN2A (bolded text.) B) The CDKN2A-correlated genes were over representative for several KEGG pathways in cancer and the cell cycle including “DNA replication”, “p53 signaling”, and “cell cycle.”

Figure 3

doi: https://doi.org/10.1371/journal.pone.0090408.g003