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Optimization and In Vivo Toxicity Evaluation of G4.5 Pamam Dendrimer-Risperidone Complexes

Figure 12

Immunohistochemistry images of spinal cord tissue.

Tyrosine hydroxylase, labeled with Cy2 (green), and Calretinin, labeled with Cy3 (red). A) control, B) risperidone (Risp) at 4 dpf, C) Risp at 6 dpf, D) DG4.5-Risp at 4 dpf, and E) DG4.5-Risp at 6 dpf. Larvae were analyzed three times (n = 3) at 10 dpf.

Figure 12