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The Prognostic Implications of Macrophages Expressing Proliferating Cell Nuclear Antigen in Breast Cancer Depend on Immune Context

Figure 6

Kaplan-Meier plots of recurrence free survival in breast cancer patients from the validation set predicted by the Tc/ClassII immune signature score in conjunction with the PCNA+ TAMs surrogate score.

(A) Kaplan-Meier curves for RFS comparing patients with a high PCNA+ TAMs surrogate score and a low Tc/ClassII score (n=59) to all other patients (n=366). (B) Kaplan-Meier curves for RFS in hormone receptor negative cases only; high PCNA+ TAMs surrogate score and a low Tc/ClassII score (n=30) to all other HR negative cases (n=123). Differences between groups were assessed using the log rank test, with p values indicated in each plot.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0079114.g006