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Glioma IL13Rα2 Is Associated with Mesenchymal Signature Gene Expression and Poor Patient Prognosis

Figure 4

Over-expression of IL13Rα2 is associated with decreased patient survival.

(A) Kaplan-Meier survival plot for patients with GBM segregated based on ‘high’ versus ‘low’ IL13Rα2 expression as determined using non-linear least-squares regression (Table S1 in File S1). Kaplan-Meier plots for the same patient cohort evaluated in panel (A) are segregated based on (B) mesenchymal signature gene expression or (C) proneural signature gene expression, with ’high‘ and ’low‘ expression determined by median expression level.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0077769.g004