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Possible Role of Intestinal Fatty Acid Oxidation in the Eating-Inhibitory Effect of the PPAR-α Agonist Wy-14643 in High-Fat Diet Fed Rats

Figure 6

Effects of intraperitoneal (IP) administration of Wy-14643 on lipid droplets.

The picture shows a representative photographic representation of lipid droplets (green) within the cytosol (pink) of the intestinal mucosa of the jejunum (A) of a rat treated with IP Wy-14643 (40 mg/kg/ml, right) or vehicle (1 ml/kg, DMSO: saline 70:30, left) (Color: blue = nuclei). Each bar represent median with 25th/75th percentiles of 19 rat of the number of lipid droplets (B) within the cytosol [cytosol expressed as area per pixel (px2)] and the area occupied by lipid droplets (C) of the liver and intestinal mucosa in percent. * Significantly different from vehicle (P< 0.05).

Figure 6

doi: https://doi.org/10.1371/journal.pone.0074869.g006