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Improved Bone Morphogenetic Protein-2 Retention in an Injectable Collagen Matrix Using Bifunctional Peptides

Figure 2

BMP-2 Binding Peptides Containing Motif 1 Isolated from Selections Using the Focused Libraries.

Biotinylated BMP-2 was immobilized on streptavidin-coated plates and subjected to multiple rounds of phage display selections using the focused libraries. Peptides which contain motif 1 were aligned. Amino acids which are present in over half of the aligned sequences at a given position are highlighted.

Figure 2