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Prenatal Exposure to Dexamethasone in the Mouse Alters Cardiac Growth Patterns and Increases Pulse Pressure in Aged Male Offspring

Figure 5

Effects of dexamethasone exposure on nephron number and cardiomyocyte number.

The number of nephrons in the kidney (A), and the number of cardiomyocytes (B) in the heart from aged male mice were assessed by unbiased stereology. Open bar indicates SAL exposed animals and the closed bar DEX exposed animals. Data is presented as mean ± SEM. N = 6 kidneys per group and N = 5 hearts per group (one animal per litter). * P<0.05, # P<0.0001 by unpaired Student's t-test.

Figure 5