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Effects of Late Administration of Pentoxifylline and Tocotrienols in an Image-Guided Rat Model of Localized Heart Irradiation

Figure 6

Analysis of collagen deposition at 6 months after irradiation.

Radiation caused increases in interstitial collagen, as measured by interstitial areas staining positive with Sirius Red. Interstitial collagen areas were not altered by PTX or TSB. Average ± SEM, n=8-9. *Significant difference with sham-irradiation (p<0.05).

Figure 6

doi: https://doi.org/10.1371/journal.pone.0068762.g006