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Extension of Drosophila Lifespan by Rhodiola rosea through a Mechanism Independent from Dietary Restriction

Figure 1

Extension of lifespan by Rhodiola rosea independent of dietary yeast content.

A and B. R. rosea feeding increased both mean lifespan and C and D, maximum lifespans in both sexes. The magnitude of mean lifespan increase for each dietary group are as follows: Males: 0.1%: 25%; 0.3%: 31%; 1%: 14%; 3%: 24%; 9%: 40%; Females: 0.1%: 16%; 0.3%: 16%; 1%: 13%; 3%: 24%; 9%: 36%. **P<0.001, ***P<0.0001, Mann-Whitney nonparametric test. Sample sizes for the control groups and treated groups respectively were as follows: Males: 0.1%: 120, 105; 0.3%: 112, 111; 1%: 110, 114; 3%: 116, 100; 9%: 99, 108; Females: 0.1%: 103, 121; 0.3%: 104, 112; 1%: 112, 105; 3%: 107, 122; 9%: 117, 121.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0063886.g001