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Relating the Bipolar Spectrum to Dysregulation of Behavioural Activation: A Perspective from Dynamical Modelling

Figure 8

Signal-to-noise ratios on the global scale (, analysed on the full time scale data) versus the signal-to-noise ratios on the scale of averaging windows (, analysed on moving windows with width 7 days applied successively on the full time scale data) for given values of n with event noise .

For lower , noise is similar on the global and on the smaller scales. For values of , this ratio changes drastically towards lower noise on the smaller scale. This indicates that noise in the system is able to generate episodes (switch between behavioural activity states) rather than only fluctuations around one fixed point. Also, solutions are less noisy around a given steady state for close below bifurcation values than for further below bifurcation values. Data points refer to the average value of SNRs, obtained by 25 stochastic simulations per value of , giving a duration of 2 years per time course.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0063345.g008