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Enterococcus faecalis Infection Causes Inflammation, Intracellular Oxphos-Independent ROS Production, and DNA Damage in Human Gastric Cancer Cells

Figure 3

E. faecalis infection increased mitochondrial mutations in MKN74 cells.

Mutations detected in the mtDNA D-loop region after infection. MKN74 cells were infected with E. faecalis at MOI 10 for 5 days. Infected MKN74 cell cultures had a significantly higher number of total mutations and transition mutations than non-infected control cell cultures. * denotes significantly different from untreated cells p<0.05.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0063147.g003