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Effects of Reduced Weight Maintenance and Leptin Repletion on Functional Connectivity of the Hypothalamus in Obese Humans

Figure 2

Increased functional connectivity in the reduced-weight maintenance with leptin repletion comparison.

Brain areas showing significant increases in functional connectivity with the hypothalamic seed (indicated in green) are shown on standard space axial brain slices with the color indicating the Z score per the color gradient on the bottom. SupLOC (superior division of Lateral Occipital Cortex), inf LOC (inferior division of the Lateral Occipital Cortex).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0059114.g002