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The Systemic Cytokine Environment Is Permanently Altered in Multiple Myeloma

Figure 1

Expression of systemic cytokines in healthy donors changes with age.

Expression of 25 cytokines was measured utilizing multiplex technology of the Bio-Plex Luminex 100 XYP in the plasma of healthy adults, N1 and N2, ages 46±10 and 73±8 respectively. Differential expression of systemic cytokines between N1 and N2 populations of healthy donors (fold change >1.25 with p-values <0.05; exact values for all fold-changes and p-values are in Table 3). (A) pro-inflammatory cytokines (B) anti-inflammatory cytokines, (C) lymphocyte growth factor.

Figure 1