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Canalization and Control in Automata Networks: Body Segmentation in Drosophila melanogaster

Figure 2

Connectivity graph of the SPN model.

The fifteen genes and proteins considered in the SPN model are represented (white nodes). The incoming edges to a node originate in the nodes that are used by to determine its transition. Shaded nodes represent the spatial signals (states of WG, HH and in neighbouring cells). Note that SLP – derived from an upstream intra-cellular signal – is an input node to this network. The self-connection it has represents the steady-state assumption: . Notice also that this graph represents the fully synchronous version of the model, where modifications concerning PH and SMO have been made (see main text for details).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0055946.g002