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Overexpression of Apolipoprotein A1 in the Lung Abrogates Fibrosis in Experimental Silicosis

Figure 4

Quantification of the lung collagen and TGF levels in the ApoA1 transgenic mice.

(A) Masson’s trichrome staining of lung sections. Scale bar = 20 µm. (B) Soluble lung collagen was measured using a Sircol assay. **p<0.01 compared with the Silica group (D15 and D30). (C) The level of the active TGF-b1 in the lung was measured by ELISA. **p<0.01 compared with the Silica group (D15 and D30).

Figure 4

doi: https://doi.org/10.1371/journal.pone.0055827.g004