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Engineered Drug Resistant γδ T Cells Kill Glioblastoma Cell Lines during a Chemotherapy Challenge: A Strategy for Combining Chemo- and Immunotherapy

Figure 1

Transitory increase in stress-associated antigens on TMZ-resistant cell line U87 after exposure to TMZ.

U87 cells were cultured to confluence and incubated in media containing 100 µM TMZ. Stress antigens were assessed at the time intervals noted on the x axis by flow cytometry and the increase in median fluorescence intensity over isotype control were calculated. Data are shown as percentage increase over unmanipulated U87 cells. SD of 3 experiments are shown.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0051805.g001