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DNA-Interactive Properties of Crotamine, a Cell-Penetrating Polypeptide and a Potential Drug Carrier

Figure 4

Scatchard plots and salt dependence of the data in Fig. 3.

A. Scatchard plot: ν ≡ [crotamine]bound/[total d(CCG)8C]p, L ≡ [crotamine]free. The solid lines represent curves calculated from the best fit of the Tsodikov et al. [35] modification of the McGhee-von Hippel model for non-cooperative binding ligands [34] (see Materials and Methods). B. Log-log dependence of the association constants calculated in panel A on [Na+].

Figure 4