Browse Subject Areas

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

< Back to Article

Immunization with a Hemagglutinin-Derived Synthetic Peptide Formulated with a CpG-DNA-Liposome Complex Induced Protection against Lethal Influenza Virus Infection in Mice

Figure 1

Location of B cell epitopes used in this study in the HA structure.

(A) Schematic representation of predicted B cell epitopes used in this study. Red, hH5N1 HA58; Green, hH5N1 HA113; Yellow, hH5N1 HA175; Orange, hH5N1 HA233. (B) Location of receptor-binding site. Red, 130-loop; Green, 190-helix; Yellow, 220-loop. (C) Schematic representation of previously reported B cell epitopes. Red, LAH; Green, H5-F10 and CR6261; Yellow, H5-1C9; Cyan, H5-1B12. The image of HA structure of the A/Duck/Singapore/3/1997 strain was created with the use of PyMOL ( and the HA structure was obtained from the Protein Data Bank (PDB: 1JSM).

Figure 1