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Predicting the Functional Effect of Amino Acid Substitutions and Indels

Figure 8

Correlation of cholesterol efflux values with the PROVEAN scores for ABCA1 variations.

In general, an increase in score (i.e. less deleterious effects) correlates with an increase in cholesterol efflux activity.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0046688.g008