Increased Cortical-Limbic Anatomical Network Connectivity in Major Depression Revealed by Diffusion Tensor Imaging
The DTI image is presented in a reconstructed color-coded tensor map, showing the direction of the principal axis of diffusion using the standard scheme. Blue codes for the superior-inferior, red for left-right, and green for anterior-posterior orientation. (1) Cortical parcellation. The DTI images are mapped with an AAL atlas in the diffusion-MRI native space. (2) Fiber tractography between ROIs. Probabilistic tractography is performed between two ROIs defined in step (1), with only direct connections being retained. (3) Whole brain anatomical network construction. All of the connections in step (2) constitute the whole brain anatomical network.