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Improved Sensitivity to Cerebral White Matter Abnormalities in Alzheimer’s Disease with Spherical Deconvolution Based Tractography

Figure 6

Segmentation of the superior longitudinal fasciculus (SLF) with DTI and CSD based fiber tractography.

Segmentation of the SLF in four patients reconstructed with DTI (yellow) and CSD (red) based fiber tractography (FT). Delineation of the SLF resulted in larger and longer pathways with CSD compared to DTI based FT. With the DTI method, fibers of the SLF were more likely to terminate at crossings between the SLF and the cortico-spinal tract in frontal regions and between the SLF and the inferior longitudinal fasciculus in temporal regions.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0044074.g006