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Empirical Validation of Pooled Whole Genome Population Re-Sequencing in Drosophila melanogaster

Figure 3

Expected and observed pooled frequency estimates.

Correlation coefficients between observed or simulated pooled allele frequency estimates and actual estimates as a function of the number of strains pooled. See Materials and Methods for a description of the libraries. Y-axis: Expected (triangles) and observed (circles) correlation coefficients of the 7 libraries compared to a perfectly binomial library, color-coded by library. X-axis: Libraries ordered by number of strains pooled.

Figure 3