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Gegenees: Fragmented Alignment of Multiple Genomes for Determining Phylogenomic Distances and Genetic Signatures Unique for Specified Target Groups

Figure 5

Signature analysis of Foot-and-Mouth Disease Virus (FMDV) serotypes.

A fragmented alignment was performed with 50/25 settings using BLASTN (BLAST+). Target groups were formulated according to the serotype definitions. All other serotypes were used as background. The ‘maximum background/average target’ setting was used for biomarker score calculation. The annotations shown come from the type Asia 1 isolate IND 13–91(DQ989312). VP1–VP4 constitutes the capsid proteins that are exposed on the virus particle and are therefore important determinants for serotype classification.

Figure 5