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How to Minimize the Attack Rate during Multiple Influenza Outbreaks in a Heterogeneous Population

Figure 4

Cumulative attack rates (CA) against the start day of intervention, in the absence of inter-group transmission (βAC = βCA = 0).

In the upper row, the denominator in the adults’ and children’s CA is the whole population (SW0 = 1); blue dotted line: CAAW; cyan broken line: CACW; red solid line: CAW = CAAW + CACW. In the lower row, the denominator in the adults’ and children’s CA is their respective proportion in the whole population (SA0 and SC0 respectively); black dotted line: CAAA; grey broken line: CACC; red solid line: CAW = S0A*CAAA + S0C*CACC. Proportion of adults in the population, from left to right: 10%, 30%, 50%, 70% and 90%. Intervention efficacy, fAA = fAC = fCA = fCC = 1. R0A = 1.25, R0C = 2; long intervention; interrupt all routes of transmission. All other parameters and initial conditions are listed in Tables 1 and 2. For the definition of the different cumulative attack rates, please refer to the Materials and Methods section, “Cumulative attack rates”, in the main text.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0036573.g004