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How to Minimize the Attack Rate during Multiple Influenza Outbreaks in a Heterogeneous Population

Figure 3

Time series of a simulated epidemic in a population in which there is no transmission between adults (black) and children (grey), in the absence (left) or presence (right) of an intervention.

Broken line: susceptible; solid line: infected. CAAW: Cumulative attack rate (adults, with whole population as the denominator); CACW: Cumulative attack rate (children, with whole population as the denominator). Infection was re-introduced into the population on day 300. The intervention (fAA = fAC = fCA = fCC = 1) started on day 100 (when the children’s epidemic is at its peak) and lasted until the first outbreak was over. βAC = βCA = 0; R0A = 1.25; R0C = 2. 50% adults; 50% children. All other parameters and initial conditions are listed in Tables 1 and 2.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0036573.g003