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A Modified Method for Whole Exome Resequencing from Minimal Amounts of Starting DNA

Figure 4

Copy number profiles estimated by deep sequencing of PCL-tumour samples, prepared using the SA- or MSA-Cap methods.

Chromosomes 1 to 22 plus X and Y are shown on the x axis. The log2 ratio of the normalized by the normal depth values for the PCL-tumour libraries is represented on the y axis. Arrows point towards the detected by deep sequencing and previously identified by SNP6 array copy number changes: gain (6p), del (6q), del (12p), del (13q) and del (17p).

Figure 4

doi: https://doi.org/10.1371/journal.pone.0032617.g004