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Mitochondria Express α7 Nicotinic Acetylcholine Receptors to Regulate Ca2+ Accumulation and Cytochrome c Release: Study on Isolated Mitochondria

Figure 5

Cytochrome c release into mitochondria supernatants.

Cyt c released from mitochondria in 2 min after addition of either 0.5 mM H2O2 or 90 µM CaCl2 in the presence or absence of DIDS or α7 nAChR ligands. Each column corresponds to M±SE of three independent measurements. Mit – mitochondria without apoptogens; Contr – mitochondria treated with H2O2 or CaCl2 only.

Figure 5