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Antitumor Effect of Malaria Parasite Infection in a Murine Lewis Lung Cancer Model through Induction of Innate and Adaptive Immunity

Figure 3

Effect of malaria parasite infection on tumor cell proliferation, apoptosis, and angiogenesis.

AC, Immunohistochemical staining (left) and assay quantification (right, n = 5–6) for Ki-67 (A), TUNEL (B), and CD31 (C) analyses of the tumor samples in Fig. 1B. Each symbol corresponds to an individual animal. The line represents the mean value. Bars: 25 µm in A, 50 µm in B and C.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0024407.g003