Local Field Potential Modeling Predicts Dense Activation in Cerebellar Granule Cells Clusters under LTP and LTD Control
(A) Simulated LFP changes in vivo obtained by changing release probability (p) alone (top) or together intrinsic excitability (IE) (bottom). The rising phase of the LFP is shown on expanded time-scale. (B) The plot shows the delay changes caused by p in T-wave. The three different curves represent levels of IE (low, normal and high). Note that appropriate LTP and LTD changes like those observed experimentally occur when both p and IE change bidirectionally around the control value. Each trace is the average of 15 simulations.