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Towards a Synthetic Chloroplast

Figure 4

Invasion of CHO cells.

A.) S. elongatus engineered with invasin and listeriolysin are able to invade CHO cells at a higher efficiency than S. elongatus harboring the empty vector or invasin alone. Cells positive for red fluorescence were sorted by FACS and B.) observed under confocal microscopy, showing intracellular localization of at least one bacterial cell per CHO cell in the majority of the cells observed.

Figure 4