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Population Genetic Analysis of Propionibacterium acnes Identifies a Subpopulation and Epidemic Clones Associated with Acne

Figure 3

Certain epidemic clones and subpopulations of P. acnes are associated with severe acne and soft tissue infections.

Percentage of prospectively collected Danish isolates from patients with moderate to severe acne (black bars) versus isolates from healthy controls (grey bars) in A), division I-1 compared to divisions I-2 and II combined; B), ST 27 compared to the rest of division I-1 among Danish isolates; and C), percentage of isolates from blood and infections in normally sterile tissues (see table S4 for details) for division I-1 compared to divisions I-2, II and III among all 143 non-redundant strains included.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0012277.g003