Luminal Flow Amplifies Stent-Based Drug Deposition in Arterial Bifurcations
Arterial drug deposition is a function of stent location. (A) Magnitude of drug concentration on the lateral wall of the main-branch within the stented region at one strut depth below the mural surface is shown. All the three cases of stent placement are simulated for the mean Reynolds number (Re0) evaluated in the Methods section. Drug concentration is plotted in log scale and the abscissa is normalized with respect to stent length. (B) Changes in drug concentration within the stented region of the main-branch are shown as a function of stent placement and Reynolds number. The abscissa is scaled with respect to the mean Reynolds number (Re0) evaluated in the Methods section.