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Caspase-2 Mediated Apoptotic and Necrotic Murine Macrophage Cell Death Induced by Rough Brucella abortus

Figure 7

Caspase-2 enzyme activity in infected macrophages induced by RB51 but not by S2308.

(A) Analysis of caspase-2 activities by a colorimetric assay. The asterisk (*) represents significant differences (P<0.05) compared to the medium control group. (B) Western blot analysis of precaspase-2 in infected macrophages. The numbers shown in the figure represent the amounts of procaspase-2 quantified by densitometry and normalized to the β-actin content. The data represent the means±standard deviations from three independent experiments.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0006830.g007