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Humanin: A Novel Central Regulator of Peripheral Insulin Action

Figure 8

A decline in both plasma and tissue HN levels with aging is observed in rodents and humans.

A) HN levels as assessed by ELISA, in young and old mice and B) across age in humans. C) Expression of RN in the hypothalamus and skeletal muscle of young and old rats. *Significantly different from other experimental groups, P<0.05.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0006334.g008