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Genomes2Drugs: Identifies Target Proteins and Lead Drugs from Proteome Data

Figure 1

Schema of data processing.

Genomes2Drugs is a free online resource. The web interface was written using open-source Java Enterprise Edition, BioJava 1.6 and NetBeans IDE 6.0. Input sequences are aligned against the human proteome, the PDB dataset and the DrugBank target proteins dataset. Only the best results are preserved. The resulting output files are parsed using BioJava and entered into a MySQL 5.1 database, where the results are sorted and ranked. Output XML files are generated from this data.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0006195.g001