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Mechanism of Neuronal versus Endothelial Cell Uptake of Alzheimer's Disease Amyloid β Protein

Figure 6

A–C: Accumulation of fluorescein labeled Aβ40 (F-Aβ40) and Dil labeled low density lipoprotein (Dil-LDL) in the late endosomes of differentiated PC12 cells following a 15 min treatment. (A) F-Aβ40 uptake; (B) Uptake of Dil-LDL; (C) Superimposition of images A and B indicate only a partial co-localization, shown by the white masked areas. D: Co-localization of F-Aβ40 and Dil-LDL in differentiated PC12 cells following a 30 min treatment.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0004627.g006