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Identification and clinical implications of immune-related hub genes in psoriasis

Fig 5

Identification of immune-related hub genes.

(A) The partial likelihood deviance under per-fold cross-validation for different λ, the dashed line corresponding to the horizontal coordinate point is the optimal λ value. (B) LASSO weight coefficient profile with 1 non-zero coefficient feature selected at the optimal value of λ. (C) and (D) Two clusters comprising 17 central genes by the MCODE algorithm. (E) The top 10 genes ranked by the MCC algorithm of CytoHubba. (F) Venn diagram for different methods screening hub genes.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0347536.g005