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Stirred tank bioreactor process for chikungunya vaccine candidate VEEV-ΔC-CHIKV

Fig 5

Investigation of different feed strategies.

(A) Cell growth status in the R101 bioreactor. (B) Cell growth status in the R201 bioreactor. (C) Overview of glucose and glutamine concentrations, virus titer, and amounts of glucose and glutamine added in both bioreactors after virus inoculation. (D) Total virus concentration obtained from both bioreactors.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0344564.g005