Identification of potential biomarkers and therapeutic targets for underactive bladder based on bioinformatics analysis and experimental validation
Fig 5
The interaction network between transcription factors (TFs) and six hub genes, the co-regulatory network of TF-miRNA-hub genes, and miRNA target prediction.
(A) The TF-hub genes interaction network. The red circles represent hub genes, the light blue diamonds represent TFs interacting with hub genes, and the purple diamonds represent TFs interacting with no less than three hub genes. (B) The interaction network between TF-miRNA and six hub genes. The red circle represents the hub gene, the blue pentagon represents the miRNAs that interact with the hub gene, the yellow pentagon represents the miRNAs that interact with no less than three hub genes, the green diamond represents the TFs that interact with the hub gene, and the purple diamond represents the TFs that interact with no less than three hub genes. (C) The predictable miRNAs that interact with hub genes.