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Cuproptosis-related gene signatures define the immune microenvironment in diabetic nephropathy

Fig 2

Identification of differentially expressed genes (DEGs).

(A) The heatmap of DEGs between control samples and diabetic nephropathy (DN) samples. The abscissa represents the clustered samples, and the ordinate represents DEGs. Red indicates up-regulated expression, while blue indicates down-regulated expression. (B) Volcano of DEGs. (C) Gene Ontology (GO) enrichment analysis of up-regulated genes in DN samples. (D) Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis of up-regulated genes in DN samples. (E) Gene Ontology (GO) enrichment analysis of down-regulated genes in DN samples. (F) KEGG enrichment analysis of down-regulated genes in DN samples.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0321636.g002