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Kalopanaxsaponin A induces reactive oxygen species mediated mitochondrial dysfunction and cell membrane destruction in Candida albicans

Fig 5

Effect of different antioxidant Tu, VC and VE on the fungicidal activity of KPA.

SC5314, pretreated with or without Tu (A), VC (B) or VE (B) was exposed to 16 μg/mL of KPA for 3 h at 30°C. The number of viable cells was then determined by colony counting method. The bars indicate standard deviations. * means statistically significant difference (P < 0.05).

Fig 5

doi: https://doi.org/10.1371/journal.pone.0243066.g005