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Porcine brain extract promotes osteogenic differentiation of bone marrow derived mesenchymal stem cells and bone consolidation in a rat distraction osteogenesis model

Fig 5

Dynamic histomorphometric measurements showed more quantitative bone formation in the PBE treatment group.

(a) Arrows pointed to the Calcein and Xylenol orange labeling in representative images of two groups at week 3 and 6. (b) Quantitative measurements of dynamic histomorphometric parameters of MS/BS, MAR, BFR/BS, BFR/BV, and BFR/TV. *p< 0.05, ** p < 0.01, compared to the PBS group.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0187362.g005