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Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster

Fig 4

Mean proportion of DNA methylation across the sequenced region is dependent on genotype at rs174537.

(A) Racial differences observed in the enhancer region (African American–red; European American–blue). (B) Genotype at rs174537 affects methylation status in the enhancer region (GG–red; GT/TT–blue). (C) No statistically significant differences between African American and European American both with GG genotype. (D) No statistically significant differences between African American and European American both with GT/TT genotype.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0180903.g004